Medicines for diabetes and porphyria repurposed for triple negative breast cancer — ScienceDaily

[ad_1] An estimated 15 to 20 percent of all breast cancer patients are “triple negative.” These unfortunate women lack three crucial treatment targets — the estrogen receptor, the progesterone receptor and human epidermal growth factor receptor 2. Because they lack these targets, most triple negative patients are treated with standard chemotherapy, rather than the preferred…

Structure of elusive innate immunity protein determined — ScienceDaily

[ad_1] UT Southwestern researchers used cryo-electron microscopy (cryo-EM) to determine the near-atomic structure of the smallest membrane protein solved to date. Their work could lead to better immunotherapies in cancer and improved treatments for autoimmune diseases like lupus. Cryo-EM — the technology credited with the “resolution revolution” underway in structural biology — uses a massive…

An optimized next-generation sequencing approach provides insight to the evolutionary history of carob — ScienceDaily

[ad_1] They say you only find what you’re looking for, and that applies in population genetics as well as in life. Population genetic studies rely on scoring known, characterized variation in DNA in order to decipher the history of different populations. However, this known variation may not be sufficient to give a properly resolved picture…